A woman named Jeanne decided to take weight-loss medication to be healthier. Her husband, Javier, supported her decision. The medication helped Jeanne lose weight and feel better. But, it also changed their relationship. Javier missed the way Jeanne's body used to feel, and they stopped having sex. Sometimes, big changes like extreme weight loss can affect how people feel about each other in a relationship. Couples might struggle to adjust to the changes. It's important to talk to a doctor and understand the possible effects of weight loss medication on your relationship.